What is Appatonin ® Diet Pill? A Review

This is a short review of a diet pill with the name “Appatonin-CR ®”.

Appatonin is a registered trademark of Quality IP Holdings, LLC in CARSON CITY, NV 89701.  Covaxil, Trivestin and Estrin-D are registered trademarks of COVAXIL IP HOLDINGS, LLC , 701 South Carson Street, Suite 200 Carson City NEVADA 89701. All thoughts expressed here are my personal opinions.

I just saw a TV ad for a weight loss product named Appatonin-CR ®.  The ad stated that Appatonin is of European origin and helps a person lose weight by suppressing appetite and thus reducing caloric intake.

The name “Appatonin” appears to me to be a mashup of “appetite” and “serotonin”.  How clever.

I had not heard of this product previously.  Being the curious person that I am, I did a quick Google search to find additional details and to see what others had to say about it.  To my surprise, I was not able to find any independent reviews or information on the web about Appotonin.

Here is the sparse information I was able to find.

From the appatonin.com website:

Developed in Europe, this breakthrough, calorie-restricting compound works with your body’s internal food sensors — including your natural hunger-control switch — telling you, “Stop eating… You’ve had enough.” In other words, Appatonin restricts your caloric intake automatically so you lose weight without feeling sluggish, aggravated, and hungry all the time.

Okay, that sounds good.  But what about more details about the active ingredient?  What makes it work?  I was not able to find much on the appatonin.com website.  On the FAQ page, there is this statement:  “the Appatonin compound stimulates the body’s satiety center.”  That provides a little insight.  It supposedly makes you feel full instead of hungry.

Further down the FAQ page is this:

Q. How does it work?

A. Frankly, the regulation of caloric intake is a complex issue, and we still haven’t figured out the exact mechanism that makes the Appatonin compound so efficacious. In addition to its ability to delay gastric emptying, the evidence points to a probable hunger hormone connection which is tied to the relationship between a quartet of appetite-regulating hormones: CCK, leptin, ghrelin, and insulin. These hormones regulate our caloric need to satisfy hunger, so one theory is that the delayed gastric emptying caused by Appatonin’s key compound somehow stimulates this quartet of appetite-regulating hormones into working together more effectively.

How reassuring is that? They “still haven’t figured out” how it works.  But they have a theory, and it has something to do with the “key compound”.   What is the Key Compound?  I was not able to find that information.  All we know is that it originated in Europe, as if that makes any difference.  Maybe there is an ingredient listing on the packaging, but I am not going to plop down $135 just to read the package, which may or may not list the active ingredients.

Is it effective?  I have no idea, but the website claims it is.  The website explains that they took a group of women to an all-you-can-eat buffet.  The women who took an Appatonin pill 15 minutes before grazing the buffet consumed 20% fewer calories than the women who were given a placebo.  No mention of how many women were in this group.  Was it 2, 4, 6, 10, 20 or 100?  That makes a difference. And why were only women included?  Does the product not work for men? What were some of the other parameters of this experiment?  No details that I could find.

The Buffet Experiment is not very convincing.  Fortunately, there was also “a separate double-blind, placebo-controlled clinical trial on overweight subjects”.  Now that sounds serious. Really serious. From the website:

And Appatonin is backed by serious science. A published, peer-reviewed clinical trial showed that more than 93% of study participants who took the key Appatonin compound lost a significant amount of weight.

There you have it.  Serious Science. Proof that it works.  Unfortunately, I was not able to find any other details about this published trial.  Where is it published? I’d like to read the report. May I have a link to it, please?  Who conducted the trial? Who are the peers that reviewed the clinical trial methodology and results? When details such as these are missing, it really makes one wonder if the claim is valid.

What about the company behind Appatonin?  I was able to find that Appatonin is a registered trademark of Quality IP Holdings, LLC in Carson City, NV.

From the appatonin.com domain name registration I found this:

Registrant Organization: Quality IP Holdings, LLC
Registrant Street: 701 S Carson St
Registrant Street: Suite 200
Registrant City: Carson City
Registrant State/Province: Nevada
Registrant Postal Code: 89701

When I plugged the 701 S Carson St address in Google Maps, I see this:

A small plaza with a restaurant, a real estate office and a few other businesses.  I wasn’t able to identify suite 200, but it must be there somewhere.

Further investigation of the address 701 S Carson St, Suite 200 shows that it is the address associated with many businesses registered in Nevada.  Apparently, this address is the “Service of Process” address provided by The Corporation Trust Company of Nevada.  This company provides Registered Agent Services. From the CT website:

Businesses that form or register to do business in Nevada must have an in-state Registered Agent. CT’s expertise assures your vital state and legal documents are handled correctly.

Okay, this is beyond the extent of my knowledge, but it looks to me like a person can hire CT to create a company registered to do business in Nevada.  I guess they set up a virtual company type of thing that meets all the legal requirements, but doesn’t have a physical location.  In other words, I don’t know where the people peddling Appatonin pills are located.  Not good.  Not good at all.

On the Returns page of the appatonin.com site is a mailing address to return the product for a refund.  That address is 5742 Harold Gatty Drive, Salt Lake City, UT 84116.  This appears (on Google Maps) to be a fairly large facility with the name Basic Research.  I wonder if any of the women that took part in the Buffet Experiment are employed there?

From the Basic Research website,

Basic’s affiliated companies hold or license patents related to more than 14 formulations, including those focused on stretch marks, wrinkles, and anti-aging, as well as non-ephedra stimulant and non-stimulant weight-loss compounds.

I found some really interesting commentary about Basic Research on this website.  I highly recommend reading it before purchasing from the appatonin.com website.

In the upper left corner of the appatonin.com website is a reference to “Covaxil Laboratories”. Covaxil Laboratories apparently makes some other diet pills and supplements which go by names such as Trivestin and Estrin-D.

From another website:

The manufacturer of Estrin-D is supposedly Covaxil Laboratories. However, this was all the information we could find about the company, as there is no official webpage or even company address made available.

I used the search feature of the USPTO website and found this information for Covaxil:

(REGISTRANT) WESTERN HOLDINGS, LLC LIMITED LIABILITY JOINT STOCK COMPANY WYOMING 1821 LOGAN AVENUE CASPER WYOMING 82001
(LAST LISTED OWNER) COVAXIL IP HOLDINGS, LLC LIMITED LIABILITY COMPANY NEVADA 701 South Carson Street, Suite 200 Carson City NEVADA 89701

I’m just guessing, but maybe Covaxil Laboratories is one of the affiliate companies of Basic Research mentioned above.

In summary, I could not find much information about the Appatonin pills, nor any reviews by actual customers.  However, Appatonin seems to be connected with Basic Research, and you really should check this out.

On the appatonin.com website is a phone number and a contact form.  I would highly recommend that any potential customers contact the company with any questions before purchasing their pills at $135.  Even then, purchasing these pills without the benefit of perusing any third party reviews seems like a really bad idea.